It's right there on Page 12 of today's presentation -
AACR 2021 Presentation Highlights12The AACR presentation highlights and presents the following new data:
•Treatment with HER-Vaxx clearly demonstrates that all patients develop high levels of HER2-specific antibodies early in the treatment protocol.
•Analysis of the antibody data reveals high levels are maintained during the treatment and maintenance phases, with only minimal booster injections of HER-Vaxx required to maintain the high levels.
•The constant and high HER2 antibody levels correlate with the early separation of the Kaplan Meier (KM) Curves for overall survival (OS) and progression free survival (PFS) clinical trial endpoints. The Kaplan Meier Curve provides a recognised statistical estimation of the survival function which visually represents the probability of an event occurring for each treatment arm at a respective time interval.
•Overall, this interim data is suggestive that the treatment is effective and well tolerated with an overall survival benefit that is superior to chemotherapy alone.
Final tumour response, correlation of antibodies with tumour response, and final PFS and OS data is expected to read out in 2021
PFS Endpoint Events met on 21st April 2021; Top Line Data expected July 2021
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