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Ann: Investor Presentation, page-20

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  1. 6,434 Posts.
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    That did cross my mind as well Funkeeh, being in a Ph3 but funded until Interim analysis by the FDA (being Orphan Disease, it is possible to gain priority review for Approval to market) & Unlisted option conversion for the rest of the trial funding.

    DXB are quite regularly updating their Investor Presentation & getting the word out which is helpful to all of us, not just new investors.

    I guess the DMX-700 pre-clinical results in COPD are very compelling though & hence I am keeping an open mind on moving forward with that IP ASAP.

    Being also invested in IMU, who already had $100 mill in the bank & just raised another $80 million (a bit of a surprise to SH), it’s wise to never assume, especially when there are multiple irons in the fire with IP & we are still waiting on 2 external COVID-19 trial results here on DXB.

    If they are positive results, well who knows? REMAP-CAP may extend DMX-200 plus ARB in trials, like they have with convalescent plasma in subgroups. New data on COVID coming out.

    Recent data published by REMAP-CAP team:

    https://link.springer.com/content/pdf/10.1007/s00134-022-06869-w.pdf

    A lot of high risk patients for severe COVID (older, co-morbidity ie DKD, CKD, CVD) may already be on ARB, ACEi so would have excluded them (exclusion criteria) from recruitment onto the RAS Domain in REMAP-CAP & also I believe CLARITY trials, but not other Domains of REMAP-CAP.

    Anyway, I also hope to hear some news soon, because if an oral treatment is beneficial, it could save a lot of heartbreak & a lot of health dollars being a global issue.

    Anti-virals help, but not everyone tests positive quickly. I have had COVID-19 twice now, and obviously different “flavours” of the virus & 4 times positive cases in our household.

    Symptoms were different between infections. & negative on RAT & PCR until day 5 or 6 of symptoms, so out of that window period for anti-virals anyway, & from what I’m hearing this isn’t uncommon, especially in vaccinated people. (Please not let’s go there again, it’s personal choice or mandatory for work & new strains are vaccine evasive for becoming infected, just may not get so sick & end up in hospital) so will be getting booster shots & just deal with it at the time. Twice being infected with COVID in 4 months is enough to deal with & I don’t want it again.

    GLTAH


    Last edited by Owl vs Fox: 29/09/22
 
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