Ann: Investor Presentation, page-123

hang on a sec, nobody disputes the possibility of significant side effects with current immunological drugs used like steroids, though specialists are very used to managing them (eg using steroid sparing drugs ) so I wouldn’t exaggerate risks, not everyone succumbs to life threatening infections.
you seem to imply a synergy between iirbesartan and dimx drug. Just irbesartan or any drug from the same arb class? That may or may not be true but the flaw in that argument is that the other ccr2 inhibitors that were unsuccessful in kidney trials were also being used on background of ras blocker ( ace inhibit or arb) as they are standard care and a given.
suggesting a 10-15 year benefit or even preventing the need for kidney transplant with dimx is a massive claim…