Ann: iPPS Increases Cartilage Thickness in Phase 2 Trial, page-22

Aside from our investments in PAR, this is great news for millions of knee OA sufferers (I have grade 1 degradation myself from years of sports) globally. Demonstrated cartilage growth by trials hard to come by in treatments.

A 0.17mm increase in cartilage vs an expected 0.02mm decreases in placebo (to 0.05 P value - in a low sample size too) that tallies with an expected 0.04mm loss per year in sufferers. That's impressive.

Obviously huge variation on where you measure, age and sex, but typical healthy cartilage figures for those a little lost for context is around 2mm+. So a 0.17mm increase in six months significant.

If you don't find the statistics compelling, the images are:



Australian bio-tech investment and coverage in financial mkts is a bit crap. Fortunately the researchers practicing the science are not.