Safety has been questioned, as it should be, and accepted as reasonable.
"There are no alternative treatments" is however incorrect.
There are quite a lot of alternative treatments. There are no FDA approved treatments for children under 12 years of age, but that includes Remestemcel, since it hasn't been adequately investigated. Actually both previous randomised controlled clinical phase 3 trials failed to demonstrater efficacy in aGVHD and all the other randomised clinical trials for other indications have also failed.
There are claims by the Mesoblast that it has efficacy, but it remains to be proven. That's not likely to satisfy the shareholders who post here since they have significant financial losses and are desperate to get their money back so they would prefer the Emperor's finest clothes narrative.
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