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96.0¢ mesoblast limited

Ann: Mesoblast Phase 3 Chronic Heart Failure Results, page-280

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ddwn

12,468 Posts.

3377

15/12/20

11:18

Post #: 49584592
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Originally posted by TehBlaster: ↑

When asked about a potential further trial, Silvo states;

"Our discussions with the FDA have been, potentially meeting a mortality reduction outcome will suffice for a single trial approval in that patient population with a high mortality risk. Whilst mortality was a secondary end point and not a primary, achieving it in this order of magnitude is a very important observation that i think we will be sitting down with the FDA in close order.

Hospitalization, traditionally have been considered to be surrogate to primary end point as drugs that have been approved for Heart Failure have not been able to achieve Mortality outcomes.

I think our study suggests even more than that, It raises the possibility that heart failure hospitalisations may not even be appropriate surrogates for mortality since we've had such a strong mortality affect and i think that is what i mean when i say that this will potentially change the paradigm of how heart failure should be considered in terms of its treatment characteristics."

BULLISH!!

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How can this be read as anything other than positive - yet, the market is having a real crack at pushing down the SP - go figure!

MSB Price at posting: $3.97 Sentiment: Buy Disclosure: Held
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Last 96.0¢		Change 0.010(1.05%)		Mkt cap ! $1.096B

Open	High	Low	Value	Volume
94.5¢	97.5¢	94.0¢	$2.076M	2.161M

Buyers (Bids)

No.	Vol.	Price($)
4	162826	96.0¢

Sellers (Offers)

Price($)	Vol.	No.
97.0¢	28820	3

View Market Depth

No.	Vol.	Price($)
1	98	1.000
3	34387	0.980
1	15000	0.970
4	83526	0.960
2	25000	0.955

Price($)	Vol.	No.
0.915	13854	2
0.940	129	1
0.960	10188	2
0.970	1000	1
0.975	23110	3

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