Monepatel, why it has the upper hand. It is one of the unique molecules that passes through the BBB to treat neurodegenerative disorders. 100% of large molecules 98% small cannot. Not only Monepatel passes BBB we know it’s safety and tolerability due to prior approval. @IndexInvestor might find this interesting.
Just need liquid formulation (if same PK/PD as tablet formulation) may be considered same drug by FDA.
Ann: MND Trial Successfully Completes First Patient Cohort, page-157
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