NEU neuren pharmaceuticals limited

Ann: Neuren and Acadia expand global partnership for trofinetide, page-36

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    Many things to like in today’s announcement:
    • Generous upfront, higher than generally expected - ~A$145m payable within 10 days. Provides Neuren with more firepower to develop NNZ-2591 in Phase 3, if preferred, and a stronger negotiating position if it chooses to sell out post-Phase 2 NNZ-2591 results (which I think it will).
    • Higher royalties than for Daybue in US – mid-teens to low 20’s.
    • Higher probability now of Fragile-X being developed further, meaning more value may now be given to this asset. Analysts (and myself) had almost written off the chance of Fragile-X being advanced.
    • Welcome early update on Daybue US sales, with sales in just the second quarter to likelyreach ~A$75m.
    • Welcome early feedback of benefits from Daybue treatment already being reported by carers and healthcare providers.

    A special well done to Gerry Zhao!
 
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