Quote from Bell 2015, "We estimate that at an annual reimbursement of $100,000 per patient, Rett Syndrome would represent a US$1.6bn market and at an annual reimbursement of $125,100 per patient, Fragile X would represent a US$8.7bn market in the US alone."
Rett - 1/10,000 Females or roughly 341,000 worldwide
Fragile - 1/4000 Males and 1/6000 Females or roughly 1.44 million
Big pharma don't focus on the US alone.
Ann: Neuren completes enrolment in Rett syndrome Phase 2 trial, page-10
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