Swiss biotech ends Phase 2 study in Alzheimer's shortly after Lilly and Biogen did the same
A small Swiss biotech has terminated a mid-stage test of a new type of oral drug for people with Alzheimer’s disease, according to the federal clinical trials database.
About eight months ago, Asceneuron disclosed a $100 million Series C to advance its O-GlcNAcase (OGA) inhibitor ASN51 into a Phase 2 study. The biotech ran the trial, which was expected to take two years, for less than a month before terminating it, according to the trial’s entry in the database.....
Shortly after Asceneuron’s fundraise in July, Eli Lilly — its main competitor — said a drug in the same class failed a Phase 2 test. Then, last month, Biogen scrapped an early-stage drug in the same class.
All three companies were trying to develop OGA inhibitors, which they believed would slow or curb the buildup of tau in patients with Alzheimer’s....
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