"It’s sad to say those who have been on it for 5 yrs are beyond...

"It’s sad to say those who have been on it for 5 yrs are beyond helping."

This may be true in general, however, if I'm not mistaken - the second strongest improvement seen in TSS50 was in a patient that had been on it for 5yrs+ which, to be fair - may well represent an outlier. One 5+ yr patient also achieved SVR25 (possibly the same patient). I'm not a scientist or medical professional, so I don't know... but it may be possible that those who are 5+yrs on treatment continue to improve past the year mark on SNT-5505 (assuming they survive long enough). I certainly hope so anyway...