Ann: Notification regarding unquoted securities - MSB, page-16

I like the thinking of cool heads like yourself, who are not obsessed with short term guidance (even though that would be nice eg. to give the uninitiated some idea about the base case) for Ryoncil. That is in the bag, and the company is able to chase the much bigger prizes of (label extended) IBD, adult GVHD and even more mind bogglingly, ischemic heart failure. All in the present.

It’s a moving feast requiring executives who are super adroit and adaptive, when all these are being juggled in the most challenging environment of the last 45 years since the fall the Berlin Wall if not 100 years since the Great Depression, when the main narcissistic actor and convicted felon, hailing from his real estate developer roots, has a garbled idea of how trade works a la competitive advantage (that for instance Apple retains within his country by way of IP despite the sites of iphone manufacturing being offshore), has put a wrecking ball to global trade plumbing at the expense of America’s soft power and alliances. (See how the billionaire acolytes are in mutiny?) He is obviously treating the problem (including re-routing the plumbing) which would take decades to fix, like one of his near death experiences in his more than a couple of bankruptcies and “near jail” ones where he can just perform a Houdini trick and wriggle out of it in an instant.

What I can stay optimistic about in the midst of such uncertainty, is that the company has more opportunities or options it can count with its fingers (what about accelerating seeking approval in Europe to diversify risk) - these risks are well defined or can become better defined by the month if not week. There is also not any lack of CEOs in the market who are thinking the same and would not be thinking of alternatives to the terribly unreliable super power having a last gasp in its greatness fantasy.

However, I would fully acknowledge that each person has a different set of circumstances to manage and some may not be able to focus on the specifics.