Yes, 29 patients in the trial got excluded which doesn't help.
The mean figures might well obscure a benefit because of the high proportion who don't respond well to anti VEGF treatment
Overall it would fit the theory that prolonged treatment with anti VEGF-A agents upregulates the other VEGF receptor subtypes which are then blocked by OPT302 for further benefit
Yes, 29 patients in the trial got excluded which doesn't help....
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