Ann: PAA completes Phase 1 and files for Orphan Drug Designation, page-157

Excellent articles Quiltman and Havenots,

Havenots, you mentioned endoplasmic reticulum response and Monepantel.

Lets extrapolate that:

https://www.ncbi.nlhttps://www.ncbi.nlm.nih.gov/pmc/articles/

As Jeon et al states in this 2023 study
" evidence indicates that the ER stress pathways is strongly implicated in the pathogenesis of ALS".

Cross reference that study that Havenots placed in their last post ( same as below)


Induction of endoplasmic reticulum stress is associated with the anti-tumor activity of monepantel across cancer types.
Tiffany J Harris et al. Cancer Med. 2023

All part of the scientific Monepantel jig saw on why it works.


Kpax