Thanks @Mangoman605.
From my perspective the staged approach whilst protracted help mitigate the risk of missing primary end points and the end of 002-003. Stage 1 has now confirmed 2mg/kg x 1 and 1.5mg/kg x 2 is NOT the minimum effective dose. The known and preferred dose used in OA008, 2B and SAS of 2mg/kg x 2 is both effective and still SAFE. Interestingly also the combined n for these prior trials using 2mg/kg x 2 all showing statistical significance on primary end points being used on OA002-003 is greater than the proposed Stage 2 n.
So we now wait for FDA to confirm we're good to move to preferred and known dosage of 2mg/kg x 2 for Stage 2.
- Forums
- ASX - By Stock
- PAR
- Ann: PAR Successful Placement and Fully Underwritten ANREO
Ann: PAR Successful Placement and Fully Underwritten ANREO, page-192
Featured News
Add PAR (ASX) to my watchlist
(20min delay)
|
|||||
Last
24.5¢ |
Change
0.000(0.00%) |
Mkt cap ! $85.7M |
Open | High | Low | Value | Volume |
24.5¢ | 24.5¢ | 24.5¢ | $31.10K | 126.9K |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
6 | 146333 | 24.5¢ |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
25.0¢ | 50464 | 4 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
6 | 146333 | 0.245 |
19 | 201272 | 0.240 |
7 | 121562 | 0.235 |
10 | 137454 | 0.230 |
1 | 50000 | 0.225 |
Price($) | Vol. | No. |
---|---|---|
0.250 | 13500 | 2 |
0.255 | 13554 | 3 |
0.260 | 67054 | 4 |
0.265 | 32500 | 3 |
0.270 | 37073 | 4 |
Last trade - 16.10pm 07/06/2024 (20 minute delay) ? |
|
|||||
Last
25.0¢ |
  |
Change
0.000 ( 2.04 %) |
|||
Open | High | Low | Volume | ||
24.5¢ | 25.0¢ | 24.5¢ | 58268 | ||
Last updated 15.27pm 07/06/2024 ? |
Featured News
PAR (ASX) Chart |