PAR paradigm biopharmaceuticals limited..

Ann: Paradigm Secures Ethics Approval for Phase 3 Trial, page-48

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    Ox, 50% dosed +112 days to reach the data required for IA, no? If required, the remaining 50% should only add a few more months to the timeline, since everything trial-related should be up and running steady-state by that stage. You're right though, that'll likely not be early 2026.

    https://hotcopper.com.au/data/attachments/6838/6838810-ae55a6f2f2654f44e40f7ae5185ecbcf.jpg

    ^According to this AGM slide, that 50% is targeted for recruitment in 2H CY2025. Dosing takes 39 days, then add 112 for IA. In total, roughly 5 months after we get notification of 50% recruitment, we'll have the data for IA. Not sure how long after the data is collected before readout. Probably give it another month at least, so 6 months after 50% recruitment.

    2H is a big period, so if (in a world first) PAR over-deliver and achieve this in July, the +6 months is January 2026. I reckon thats wildly optimistic, and we should measure from 31st December 2025, giving us a readout around July 2026. We can set our watches with a lot more certainty when we get notification of 50% recruitment though.
 
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