In all recent timelines they’ve clearly said Tox studies would start in Q4. That hasn’t changed since they finished the engineering run. We’re just over one month into the quarter, why would you need to email about it?
I could understand wanting to email if there was no tox update by Christmas because then they’d be unlikely to start tox studies until the new year and that would be a delay. Have some patience. You’ll need plenty more of it in the next year
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