PYC pyc therapeutics limited

Ann: Peer Reviewed Journal Publication, page-9

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    probably should have added this from the article at head of last post...

    Quote:
    To investigate whether FPPa-OmoMYC was able to sensitize TNBC cells to chemotherapy, four chemotherapeutic drugs commonly used in the clinic for the treatment of metastatic cancers, including breast [65,66,67] and head and neck carcinoma [68] were chosen (taxane: docetaxel; anthracycline: doxorubicin; epidermal growth factor receptor (EGFR): erlotinib; and monoclonal antibody: cetuximab). These inhibitors were tested alone or in combination with FPPa-OmoMYC (Fig. 4a–d). We found that T11 and SUM149 cells responded to the combinations of docetaxel + FPPa-OmoMYC and cetuximab + FPPa-OmoMYC, respectively, with a combination index (CI) lower than 1, indicating highly synergistic interactions (Fig. 4a and d right).
 
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