"Bile duct cancers are difficult to treat and typically respond poorly to immunotherapy
drugs. Pseudoprogression is a phenomenon in which the cancer initially appears to be
growing, largely due to the cancer cells being infected by the virus then followed by
infiltration of cancer fighting immune cells. However, it is usually followed by a decrease in
tumour burden when the therapy takes effect. This phenomenon can benefit patients
receiving immunotherapy but often leads to premature discontinuation of treatment
owing to the false impression the cancer is growing.
I can remember Ex-Director Axel Hoos describing it many years ago when referring to the first T-cell vaxx, why had this high caliber man to go?
Anyway, nobody can say YF / SP / LC / NE overpromised. And we are talking about patients who had several lines of treatment, not like many other bios who test their drugs on stage 1 or 2.
If that doesn't get big pharma's attention what else will?
GLTA
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