Yeah I was surprised by the design as well, but I’m sure they’ve worked out pre-clinically what level of CF33-CD19 is adequate for getting good coverage of CD19 on the tumours.
latest publication on the preclinical work -
https://pubmed.ncbi.nlm.nih.gov/38214445/
Ann: Phase 1 onCARlytics Trial Advances to Combination Arm, page-38
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