Ann: Phase 2a Study Shows BTX 1801 Eradicates S. Aureus, page-863

First 863 Last

Share
Profile

Follow
bernsta

4,391 Posts.

1368

10/02/21

22:55

Post #: 50878002
Share

Originally posted by bigfella195: ↑

When the 1801 results were announced I was pleased that the primary endpoints had been achieved but was left with a few questions. I popped off an email to Botanix and this morning was able to get some answers. They could not have been any more open and forth coming, very appreciative. Thought I would share some insights:

- All 66 participants completed the trial. The participants were tested 3 times prior to the trial to determine if they had Staph Aureus. If they did not have a staph infection on the third test their data was not included and hence the percentages (A post yesterday clarified the calculations).

- There was no data collected at the end of day 5 as the trial was set up around the protocols of trials completed for other nasal decolonization products.

- 2 participants had MRSA, too few to be considered statistically significant. 1 in the vehicle group and 1 in the ointment group. The MRSA in the vehicle group was not eliminated, while the MRSA in the ointment group was successfully eliminated. Botanix had hoped there would be more MRSA cases.

- Side effects were really very mild, a little crustiness in some cases.

- The ASX no longer allow pharmaceutical companies to present comparisons with other company’s trials in announcements.

- The level of nasal staph was coded as eliminated, light, moderate or high. Data about staph levels in participants who were not classified as eliminated is still to come through.

- Participants who were recolognised by staph had there staph treated again and the staph was, in all cases, still susceptible suggesting no resistance development.

- In terms of recolognisation, staph is carried on many parts of the body and persistent carriers recolognize a lot. Other nasal decolonization studies gave participants full body chlorhexadine washes prior to the trial, something that was not done in Botanix’s trial.

- More data about the 1801 trial is still to come in.

-Matt Callaghan will be presenting remotely at a conference next week and hopefully will provide more data about the trial.

It is clear to me that Botanix genuinely believe the data is very good and compares well to competitors in the staph decolonization space, dialysis is one area they think this has some real potential.

My doubts about the results, based on some basic Google searches of other trials, were completely allayed. IMO Botanix is on to something and I’m not selling any time soon. Look forward to Matt’s presentation next week.

Expand

Great post again mate.

Be nice if this was further communicated in the announcements. Shareholder are left wanting more clarification. We are just battlers having a go.

BOT Price at posting: 15.0¢ Sentiment: Buy Disclosure: Held
13 Upvote

1 Great analysis

Reply

Top Stories

Biden's exit bakes in a Kamala Harris ballot while markets expect Trump to win. How could equities fare this week?

SPR

Dalgaranga gold play's increase in MRE a 'pivotal moment' for Spartan

EMV

EMVision Medical successfully fabs first prototype of First Responder brain scan device – portable enough for a backpack

SRG

SRG Global flags FY24 earnings just short of $100M; sees 10% jump in FY25

ASX Market Open: Australian market rallies on US rebound, as tech stocks perform well, and Biden steps down

There are more pages in this discussion • 138 more messages in this thread...

First 863 Last

Add BOT (ASX) to my watchlist

(20min delay)
Last 36.0¢		Change 0.000(0.00%)		Mkt cap ! $651.6M

Open	High	Low	Value	Volume
0.0¢	0.0¢	0.0¢	$0	0

Buyers (Bids)

No.	Vol.	Price($)
1	1007	43.0¢

Sellers (Offers)

Price($)	Vol.	No.
34.5¢	25319	1

View Market Depth

No.	Vol.	Price($)
1	1007	0.430
7	124877	0.360
2	64000	0.355
3	145707	0.350
12	1715501	0.345

Price($)	Vol.	No.
0.345	25319	1
0.355	6956	2
0.360	243949	5
0.365	175700	2
0.370	252572	5

Last trade - 09.30am 23/07/2024 (20 minute delay)

BOT (ASX) Chart

Day chart unavailable

Ann: Phase 2a Study Shows BTX 1801 Eradicates S. Aureus, page-863

Biden's exit bakes in a Kamala Harris ballot while markets expect Trump to win. How could equities fare this week?

Dalgaranga gold play's increase in MRE a 'pivotal moment' for Spartan

EMVision Medical successfully fabs first prototype of First Responder brain scan device – portable enough for a backpack

SRG Global flags FY24 earnings just short of $100M; sees 10% jump in FY25

ASX Market Open: Australian market rallies on US rebound, as tech stocks perform well, and Biden steps down

Featured News

Buyers (Bids)

Sellers (Offers)

Featured News

Ann: Phase 2a Study Shows BTX 1801 Eradicates S. Aureus, page-863

Top Stories

Biden's exit bakes in a Kamala Harris ballot while markets expect Trump to win. How could equities fare this week?

Dalgaranga gold play's increase in MRE a 'pivotal moment' for Spartan

EMVision Medical successfully fabs first prototype of First Responder brain scan device – portable enough for a backpack

SRG Global flags FY24 earnings just short of $100M; sees 10% jump in FY25

ASX Market Open: Australian market rallies on US rebound, as tech stocks perform well, and Biden steps down

Featured News

Buyers (Bids)

Sellers (Offers)

Featured News