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Ann: Phase IIb Dog Trial Achieves Interim Clinical Endpoints, page-35

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  1. 2,773 Posts.
    lightbulb Created with Sketch. 1518
    So help me decipher...

    Overall, including phase 2a and 2b :

    15 dogs enrolled.

    3 of the 15 were withdrawn as too far gone and MPL didn't help. (Good info to know, treat early.)

    1 of the remaining 12 had objective regression.
    6 of the remaining 12 has objective stable disease.

    12 of 12 completed the 28 day trial. So that leaves me with 5 unaccounted for. All I can assume is because they were not either objective regression or stable, they completed the course of treatment but it had little effect (and therefore may have had the same outcome if untreated).

    So is it fair to say 7 out of 15 had a successful outcome with MPL. If so that sounds ok but I am unsure what that is like in comparison to current standards of care. Any vets know?

    Also is it an assumption that this has somewhat disproven the biphasic hypothesis? Also good to know.
 
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