Well this is the best news in a long while...
"
In an oral presentation, Prof. Adnan Khattak, Consultant Medical Oncologist at Fiona Stanley Hospital and a principal investigator of the on-going TACTI-mel study, showed efficacy and safety data from 18 patients in part A, the dose escalation part of the study, and first safety data from 6 patients in part B.
In part A, dose escalation, combination therapy started after four cycles of KEYTRUDA® monotherapy. In part B, patients were treated with the combination from the first day of treatment i.e. receiving efti from day one, cycle one with KEYTRUDA®.
The efficacy data from part A was encouraging and supportive of previously disclosed response rates with a 33% Overall Response Rate (ORR) when measured from start of the combination at cycle 5 of KEYTRUDA®. The ORR was 61% when measured from the start of KEYTRUDA® monotherapy treatment in an explorative analysis measuring from cycle 1, day 1. A disease control rate of 66% was reported from the combination treatment. The patient population was partly pre-treated before the start of KEYTRUDA®, suboptimally responding to KEYTRUDA® and the majority had increased risk factors.
In both parts (A and B), combination therapy has been well tolerated with no dose-limiting toxicities and local erythema and injection site reactions as the most common side effects. Importantly the safety data of part B supports the dose scheduling of the Company’s planned Phase II TACTI-002 clinical study in collaboration with MSD."end
It works...its safe..and we are now on the world stage. Great things will follow.
- Forums
- ASX - By Stock
- Ann: Positive interim TACTI-mel data presented at SITC
Well this is the best news in a long while... " In an oral...
-
- There are more pages in this discussion • 50 more messages in this thread...
You’re viewing a single post only. To view the entire thread just sign in or Join Now (FREE)
Featured News
Add IMM (ASX) to my watchlist
|
|||||
Last
36.5¢ |
Change
-0.005(1.35%) |
Mkt cap ! $530.2M |
Open | High | Low | Value | Volume |
36.5¢ | 37.0¢ | 35.5¢ | $328.0K | 909.1K |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
2 | 38094 | 35.5¢ |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
36.5¢ | 29559 | 4 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
2 | 38094 | 0.355 |
8 | 199832 | 0.350 |
4 | 23669 | 0.345 |
3 | 50293 | 0.340 |
4 | 44001 | 0.335 |
Price($) | Vol. | No. |
---|---|---|
0.365 | 29559 | 4 |
0.370 | 132586 | 4 |
0.375 | 59586 | 3 |
0.380 | 79650 | 3 |
0.385 | 101562 | 6 |
Last trade - 16.10pm 26/08/2024 (20 minute delay) ? |
Featured News
IMM (ASX) Chart |