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Ann: Positive Preliminary Results from SMARTCOUGH-C-2 Study, page-165

Currently unlisted. Proposed listing date: 4 SEPTEMBER 2024 #

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Davisite

19,345 Posts.

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30/10/18

11:49

Post #: 36312249
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Originally posted by starsky ↑

The thing that I was struck by is the commenatr on the clinical diagnosis.

" The clinical diagnosis was made by an independent, centralised clinical adjudication committee using all available clinical data, including radiology and microbiology. In the case of 429 patients (33% of the total) agreement on the clinical diagnosis was not reached between two adjudicators and a third adjudicator was required to reach a majority consensus".

That has nothing to do with the resapp test... that's the current clinical testing!!!

Put Resapp to one side.

For 1 in 3 patients, two doctors with a full suite of tests, in including Radiology (Xray/CT scan?) and microbiology test results couldn't agree on the clinical diagnosis for the patient!

In that scenario - the doctors are probably only 50:50 on a clincally correct diagnosis for 33% of patients...

In that context - I now understand why the test results PPA and NPA are as low as they are....

The App may actually be more accurate than the doctors, but the doctor's can't get it right!

How the hell could you actually know ?

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Yes this is all true, but this just points to a terrible trial design. Given this level of disagreement they should have had a three doctors reviewing all cases.

RAP Price at posting: 11.0¢ Sentiment: Hold Disclosure: Not Held
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