Not "limit", rather "efficacy":
Once we hit 4000mg, assuming there are no clinical adverse reactions, we could (technically) successfully treat a subject that has sepsis.
I think this will attract widespread attention, as from this point on Recce 327 starts to look less like a risk, and more like an opportunity. i.e. F.O.M.O. will build.
All I.M.O. of course.
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