Ann: PTX100 Ph1b results to be presented at specialist congress, page-15

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DerrickJ

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22/04/24

12:00

Post #: 73454812
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Originally posted by Shellbell: ↑

It's certainly not looking that way. I'm a little surprised that management hasn't seized the opportunity to announce the final data officially given the additional PR/CR recorded.

What I did find, though, was another co. that presented at the WCCL meeting. Initially, I was startled by the existence of a rival in the field of CTCL. However, Resminostat is described as a "maintenance" therapy and whilst the data seems impressive, the Progression Free duration for those in the placebo group seems exceptionally long.

https://www.4sc.com/product-pipeline/resminostat/In visiting their website, it appears (if I have interpreted it correctly) that the trial involves patients with less advanced CTCL than what PTX-100 has been treating. PTX-100 has only been tested on patients who have failed between 3 and 6 prior lines of treatment.

https://www.4sc.com/news/4sc-ag-resmain-trial-meets-primary-endpoint-in-cutaneous-t-cell-lymphoma-ctcl/

Not sure what this means: "Given that the RESMAIN study did not meet its key secondary objective, 4SC will now approach the European Medicines Agency in order to better understand the feasibility of submitting a Marketing Authorization Application."

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Nice find shell! Certainly seems like a very tricky cancer to cure given the fact that this 4SC is pursuing a “maintenance” therapy as opposed to a potential cure (ptx-100).

I found these two paragraphs that further clarify the trial.

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Ann: PTX100 Ph1b results to be presented at specialist congress, page-15

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