Thanks Zig, it seems significant changes can be interpreted off in many tangents as evidenced by our postings from your original post
In hindsight (to an outsider looking in) it could now be interpreted as a small tweak to an already announced study we thought the company was doing months ago...
But I can see (from a company insider looking out) that in can be interpreted as 'oh this is a bit bloody painful this process and it's going to be a significant change to our clinical development strategy to run this trial'
Ann: Quarterly Activities/Appendix 4C Cash Flow Report, page-45
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