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The lingo here is not just about semantics. Trials “start” when...

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    The lingo here is not just about semantics.

    Trials “start” when the first patient is consented.

    If you start a trial prior to registering it - it will not be prospective.

    If you start a trial prior to IRB approval you will be in the doo doo.

    Engaging a CRO and talking to potential sites are preparatory activities prior to starting a trial. So basically preparatory activities are "underway".
 
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