Based on public messages from Alan and also when I spoke to him 1:1 at a conference in Sydney in November Alan has always said that they will not give a patient an extra dose just because the trial design says 4 doses if the patient is showing nearly full response in 1, 2 or 3 doses. Similarly they will not give patients a higher dose if they are responding at a lower dose level. This is how clinicians will treat their patients in the real world. So I guess we just have to wait for announcements to know how they went with the trials and which would be patient response based instead of a blanket regimen.
This is IMHO only and I could be wrong. DYOR.
Ann: Quarterly Activities/Appendix 4C Cash Flow Report, page-16
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