Yes definitely a good idea to chat to a diabetes expert to see what will give you the most bang for your buck in terms of an add on measurement that is not too much extra burden (for participant and researcher) but that will also be as clinically meaningful as possible.
I would imagine the ideal person would be an endocrinologist who has current experience in clinical diabetes research. That would give them a sophisticated perspective on what's clinically meaningful vs what is practical. Anyone here know anyone that might fit the bill, a researcher at a diabetes clinic?
Is it practical to measure insulin and C-peptide after an overnight fast in this study for example, and what is the best way to track medication intake.
Some of these additions may also require an ethics amendment, which can take time. Although depending on the original submission they may not, like if blood is already being taken and there is a statement in the informed consent stating that blood may be analysed for this research as well as related research by the same researchers/company. Such statements can be very helpful to have in the informed consent.
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