PAR paradigm biopharmaceuticals limited..

Ann: Quarterly Update and Appendix 4C - quarterly, page-9

  1. 288 Posts.
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    Have we seen the reporting of the ARDS post infection treatment data before? I don't think I have noticed this reported before at least. It sounds like the PPS may be very good at taming the cytokine storm of the Covid 19 post viral stages. Given we are going to be living with endemic Covid for years I reckon this could be big.

    Positive Top-line Results in ARDS Preclinical Study: PPS at the post-acute phase of viral
    infection (21-days post infection) demonstrated a statistically significant reduction in
    pulmonary collagen compared to vehicle treated groups based on histological staining of
    collagen. PPS administered subcutaneously at Day 0 at 3mg/kg resulted in a statistically
    significant reduction in inflammatory cell infiltrates in the lungs at 8 days post infection.
    Last edited by Grainger: 31/01/22
 
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