The answer to that is yes and no. It is intended that some trials will be run using a biomarker to recruit and others only looking at the correlation between FTO and a response as a secondary endpoint at the end of the trial.
The upcoming EMD AML Stratum 2 trial will not be recruiting on the basis of a biomarker other than being EMD AML positive.
Ann: Race executes Israel AML Phase 2 Trial Contract, page-58
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