Ann: Results of LCT Parkinsons trial require further analysis, page-108

i apologize if i'm repeating what's in previous posts, just too many to read. bottom line, NTCELL is useless for treating pd. it's as clear as glass to me based on these results. they inserted twice the NTCELL40 in phase2b than they did in phase1 and got about the same results. in the cc it was stated they have 14month data for the NTCELL40 group and 10.5month data for the NTCELL80 group but they didn't mention it, i assume it wasn't any better.

i was blinded by greed. the fact that there were no side affects even at the higher dose should have been an early indication that NTCELL doesnt help much, if it was really rejuvenating nerve cells you'd expect some increase dyskinesias, involuntary movements caused by getting too much dopamine, and they would have had to decrease meds. during the cc it was said noone changed their drug regime.

they needed a really big affect to get it approved and they got none, a bigger study won't help imho.

here's 2 similar studies showing how strong the placebo affect is in pd'ers
there's been at least 6 studies drilling sham holes and inserting either cells or genes into pd'ers brains and all followed the pattern that occurred with LCT - great phase1, failed phase2 once you add a control and blind the treatments. there is a huge placebo affect with pd'ers, the population of pd'ers willing to undergo the risks of irreversible placement of living genes/cells thru a hole in your head seem to have an extraordinary placebo affect, it's almost self selecting.

1. spheramine
https://www.michaeljfox.org/foundation/publication-detail.html?id=76&category=3
2. neurturin
https://www.michaeljfox.org/foundat...rial-of-cere-120-yields-disappointing-results
3. gdnf - there was a book written about the failed phase2
https://scienceofparkinsons.com/2015/12/22/gdnf-and-parkinsons-disease/
https://scienceofparkinsons.com/2016/07/07/the-gdnf-trial-bristol-initial-results/

LCT doesn't work in a vacuum, they knew about all the previous failures and the slim odds they would get a positive phase2b. this was a small study that got way overhyped on this board imho. i hope LCT can survive, i sold all my shares this morning, there's always another trade.