whytee, you mention responsiveness to l-dopa. during the cc it...

whytee, you mention responsiveness to l-dopa. during the cc it was mentioned that all the patients in the phase1 trial had been approved for DBS and 1 criteria for that is good l-dopa responsiveness. it was stated all patients in phase2 had been diagnosed at least 5 years ago, under 65 and were heading towards getting a DBS eventually which implies L-DOPA responsiveness, i'm sure they must have measured them ON and OFF in the UPDRS motor test to make sure the responded well to l-dopa. you take the test 10hrs after your last meds, then take your meds and re-test 90minutes later. i assume they tried to select patients that didn't have atypical parkinson's. if you go to a parkinson's support group you'll quickly see no 2 pd'ers are alike.