Ann: Ryoncil Commercial Launch Update and Product Pipeline, page-215

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    This is straight from the PR:

    "SURVIVAL in adults with SR-aGVHD who have failed at least one additional agent, such as ruxolitinib,
    remains as low as 20-30% by 100 days.1,2 In contrast, 100-day SURVIVAL was 73% after Ryoncil®"

    So, survival vs survival. A direct comparison of rux vs rem-l efficacy would require an RCT that has never been done. I don’t believe the company is trying to make such a comparison. Rather, they've ceded the secondary therapy slot to ruxilitinib, at least for the time being.
 
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