For approved indications the dosage varies depending on the indication:
https://www.merck.com/product/usa/pi_circulars/k/keytruda/keytruda_pi.pdf
Use for unapproved indications is a medical judgement (note - doctors make the judgement call based on preliminary data):
https://www.fda.gov/patients/learn-...rstanding-unapproved-use-approved-drugs-label
Ann: SPP Closing Deadline Reminder & Investor Briefing Recording, page-53
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