Thanks Daon
BMS - 'Relativity' trial data - PFS for Relatlimab/Opdivo is over double that of Opdivo mono.
A fantastic result!!
BMS CEO said in recent teleconference that they were excited by LAG-3 and now can see why. They have many more LAG-3 trials in progress at P1/2 stage. This is first completed P3 trial for LAG3/PD1 combo as a first line therapy.
They will now be in talks with FDA to 'fast track' above combo.
Whilst Relatilimab is a different mode of action (anti- LAG3 blocking) to that of Efti, we know that OS (durability) could be better statistically than PFS (see AIPAC initial PFS v OS data).
If TACTI-002 posters show improving data (combo's with Keytruda) then we are off to the races!
Competitive tension building......
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