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clock Created with Sketch. 11/12/19
13:39
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Originally posted by Al.:
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There’s 80k + eyes on these threads thought I would share an analogy for small molecule cancer therapies - imagine the human body is like a house. Cancer is A hostile army / predator that seeks to enter and destroy the house. Small molecules act by closing down the entry points for the enemy. They cannot destroy the enemy alone - chemotherapy in this case is like the police / machine gun that comes into play to destroy the approaching army. The small molecules close the doors and windows (either by stopping cell division, proliferation other survival pathways or by activating or highlighting the cancer cells for the immune system.) Each persons body could be likened to a different house design eg some are apartments / some are duplexes, some have skylights, backdoors ect. In medical speak these would be referred to as ‘markers’ or biology specific to person DNA, epigenetic expression or specific type of cancer.
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your exactly right , chemo is front line attack but a multi pronged attack is where good results are seen , I’m currently on a 18 month stint of chemo and take rso high potency thc oil , I’ve stopped taking it twice over that 18 months and both times my tumour markers have started to increase , I’m super excited to see how this car t treatment develops , crispr is another exciting field for cancer treatment
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