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$1.05 mesoblast limited

Ann: Third Quarter Results Presentation, page-51

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Hharry

46 Posts.

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28/05/20

09:44

Post #: 44885134
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Originally posted by wot: ↑

Fill in the blacks. May, primary endpoint 30 days later, interim analysis at 30% - meaning a readout is theoretically possible within 10-14 days. When did we start dosing 7 May?

 Up to 300 patients randomized 1:1 to remestemcel-L or placebo
 Primary endpoint Day 30 mortality;
 First patients randomized and dosed in early May

Interim analyses planned which could result in stopping the trial early for efficacy or futility.
First interim analysis when 30% of patients reach the primary endpoint

 Recruitment is expected to complete within three to four months, with interim analyses planned which could result in stopping the trial early for efficacy or futility

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I think everyone is getting a bit ahead of themselves with timeframes of the interim report.

SI said that it will be 3 to 4 months to recruit the 300 patients. That is 2.5 - 3.3 patients per day and that’s assuming a contestant (which we all know won’t be the case as they only have 12 of the 30 hospitals on board so far.

So I’m estimating that they are treating 2 patients a day based on the above, that’s 50 days plus the 30 days to meet the primary endpoint from the treatment date.

Therefore I wouldn’t expect to see these interim results until mid July.

MSB Price at posting: $3.84 Sentiment: Hold Disclosure: Held
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