Special mention of the merits of @whytee who fiercefully defended the minority stance on HC in that OPT would report topline readout for COAST and ShORe
a) not together but separately and
b) with COAST reporting as soon as April 2025
Whytee, my respect! Definitely a risky call of yours against the entire real-world evidence of Eylea, Beovu and Faricimab. But OPT‘s need to come up with a positive trigger for sozinibercept as soon as possible seems to have forced management into your camp.
New timelines being:
1. COAST:
Full enrollment Feb 15, 2024
Primary Completion Date Feb 13, 2025
10 weeks +/- 5 days for cleaning, analyzing and presenting the data => Topline readout Apr 20-30, 2025
2. ShORe:
Full enrollment May 28, 2024
Primary Completion Date May 27, 2025
Same 10 weeks +/- 5 days for cleaning, analyzing and presenting the data => Topline readout Aug 1-10, 2025
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