Ann: Trading Halt, page-40

Thanks Rich&Poor. I think that is very interesting and insightful speculation. We know from previous reports that Matt Dun has been investigating paxalisib in various combinations so perhaps something further has come from his work (in addition to the PNOC trial). It does certainly seem like a possibility.

Extract from from the HMRI website is below.

Work by Associate Professor Dun and his colleagues has extensively informed the design of the study, in particular by research undertaken at the University of Newcastle and Hunter Medical Research Institute (HMRI). The HMRI team has conducted laboratory research with paxalisib for several years and has generated a powerful body of data combining paxalisib with other investigational drugs.