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Ann: Update - Dividend/Distribution - NEM, page-107

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    Indications

    The use of injected gold compound is indicated for rheumatoid arthritis.[4] Its uses have diminished with the advent of newer compounds such as methotrexate and because of numerous side effects.[4] The efficacy of orally administered gold is more limited than injecting the gold compounds.[5]

    Mechanism in arthritis

    The mechanism by which gold drugs affect arthritis is unknown.[5]

    Administration

    Gold-containing drugs for rheumatoid arthritis are administered by intramuscular injection but can also be administered orally (although the efficacy is low). Regular urine tests to check for protein, indicating kidney damage, and blood tests are required.
 
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