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clock Created with Sketch. 04/12/23
19:29
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Originally posted by Davisite:
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There doesn't appear to be much difference by risk factors in how much damage anthracyclines cause the heart, where the difference shows up is those with other cardiac risk factors are more likely to end up functionally disabled from the damage. The best explanation of this is those with cardiac risk factors have less spare capacity so that even limited damage can result in very serious health impacts.
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If I remember correctly, the recruitment in the AML EMD trial was a problem becasue it took into account some information from KOLs that turned out to be inaccurate (that EMD was or could be screened in AML patients).
Last edited by
ReNova :
04/12/23
(20min delay)