Not that I can go into details at this time, but your timeline is not accurate. The timelines based around the options give a better estimate.
The phase 1 is open label and because of the Bayesian trial design we have the ability to do interim analysis during Phase 2. We won't be flying blind, nor waiting until 2029.
One final point that might not seem obvious is the cardiac endpoints are measured at the beginning and end of the chemotherapy treatment cycle which means the trial doesn't have to run for long time periods waiting for patients to progress or die of their cancer.
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