On the hop here … but looks pretty good to me.
The key to success was dealing with a possible placebo effect which the design took care of with a long monitoring period before participants entered the trial. Plus keeping the attrition rate very low – which they did – with only one subject lost.
The effect size (about 5-6 points) is exactly what you would hope for – not just for statistical significance but also for clinical significance.
Of-course you would want to see supporting evidence coming out from the secondaries … but so far so good.
The good design here has translated good outcomes … as I had earlier argued (hoped) it might.
So well done ZLD … will read the journal paper with interest which will provide more details to look under the hood … but overall can’t fault anything from this announcement.
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