Science Network Western Australia features an article today on PYC’s work with antimicrobial peptides.
The following information appears to be new. I especially like the last comment.
Recent tests on 50 samples from Royal Perth Hospital, including some multi-drug resistant bacteria from Bali bomb victims, showed phylomer peptides could be highly effective.
However, Dr Heinrich says much work is needed before they can be used to treat humans, as developing peptides as drugs is challenging because they are small, relatively expensive and easily filtered out of the body.
Their best application may be niche areas like catheter linings and burns wounds where patients develop multi-drug resistance infections because they spend months on antibiotics.
“In this instance you could spray them onto a wound and the issue of the peptides being easily flushed out by kidneys wouldn’t be an issue any more,” Dr Heinrich says.
She says what is most encouraging is the evidence that AMPs can rejuvenate traditional antibiotics, to which bacteria have become resistant—essentially making them effective again.
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(20min delay)