Blood Clots & Fibrous Clots
COVID-19 Vaccines: A Risk Factor for Cerebral Thrombotic Syndromes
https://www.preprints.org/manuscript/202406.1236/v1
(Study compares the rates of cerebral thrombosis among COVID-19 vaccine recipients to the large number of individuals who take an influenza vaccine annually. Compared to influenza vaccines given over 34 years, COVID-19 vaccines in 36 months of use had over 1000-fold increased risk of most blood clot events, and compared to all vaccines combined administered over 34 years, this risk remained at over 200-times greater with COVID-19 vaccination. Explanatory article here.)Extensive splanchnic vein thrombosis after SARS-CoV-2 vaccination: A Vascular Liver Disease Group (VALDIG) initiative
https://journals.lww.com/hep/abstract/9900/extensive_splanchnic_vein_thrombosis_after.747.aspx
(“in 72% of cases, no other cause for SVT could be identified following SARS-CoV-2 vaccination. These cases were different from patients with nonvaccine–related SVT, with lower incidence of prothrombotic conditions, higher rates of bowel ischemia, and poorer outcome.” Explanatory article here.)Sialylated Glycan Bindings from SARS-CoV-2 Spike Protein to Blood and Endothelial Cells Govern the Severe Morbidities of COVID-19
https://www.mdpi.com/1422-0067/24/23/17039
(Spike protein causes the clumping of blood cells, whether by infection or vaccine injection. Explanatory video here.)Safety Profiles of mRNA COVID-19 Vaccines Using World Health Organization Global Scale Database (VigiBase): A Latent Class Analysis
https://link.springer.com/article/10.1007/s40121-022-00742-5
("We found five distinguished clusters of serious AEs following mRNA COVID-19 vaccination, with a high proportion of vascular disorders, including pulmonary embolism, deep vein thrombosis, and thrombosis, along with respiratory disorders. Mainly, the number of COVID-19 vaccines administered due to the pandemic resulted in a massive number of AEs following COVID-19 vaccination.")Adverse events following COVID-19 mRNA vaccines: A systematic review of cardiovascular complication, thrombosis, and thrombocytopenia
https://onlinelibrary.wiley.com/doi/10.1002/iid3.807
(“Cardiovascular (CV) events such as thrombosis [most common], thrombocytopenia, stroke [most common after Moderna], and myocarditis frequently occur with the mRNA vaccines studied. A significant number of studies included in our review reported BNT162b2 events, which presses the need to conduct more research into the CV implications of mRNA-1273 (Moderna) vaccine.” Keep in mind usually <50 deaths with a widely used, novel product prompts a worldwide recall. To have 284 well described deaths in one year as a result of cardiovascular and or thrombotic complications is a striking finding in the medical literature for products that are still on the market and promoted by public health agencies all over the world. Explanatory article here.)Thrombosis Development After mRNA COVID-19 Vaccine Administration: A Case Series
https://assets.cureus.com/uploads/case_report/pdf/166699/20230803-25065-1ra698e.pdf
(“Thrombosis associated with mRNA-derived vaccines is not yet recognized as a separate entity by formal societies. As a result, no clear guidelines or expert opinions exist on the ideal management.”)Thromboembolic Events after COVID-19 Vaccination: An Italian Retrospective Real-World Safety Study
https://www.mdpi.com/2076-393X/11/10/1575
(Both Pfizer and Moderna cause blood clots at similar rates, although Moderna causes more pulmonary emboli and Pfizer more leg clots. For Pfizer & Moderna, women account for 70% of blood clots. Moderna had 7.1 thromboembolic events per 100,000 doses, Pfizer 7.6 per 100,000. [J&J and AstraZeneca were 5-6x that amount.] “We may have underestimated rates of thrombotic adverse events”)Incidence and outcomes of splanchnic vein thrombosis after diagnosis of COVID-19 or COVID-19 vaccination: a systematic review and meta-analysis
https://link.springer.com/article/10.1007/s11239-022-02732-3
(Because the Spike protein on the surface of SARS-CoV-2 causes blood clotting, most venous thromboembolic syndromes are seen in both COVID-19 patients and those who took the vaccines. It is likely that the highest risk patients are those who have cumulatively been exposed to the Spike protein via multiple injections and one or more occurrences of COVID-19 illness. Explanatory article here.)Factors associated with stroke after COVID-19 vaccination: a statewide analysis
https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1199745/full
(A statewide study that followed 5 million people living in Georgia found that those who contracted COVID-19 within 21 days of vaccination were at the highest risk of stroke.)Cancer
SARS-CoV-2 Vaccination and the Multi-Hit Hypothesis of Oncogenesishttps://www.cureus.com/articles/209584-sars-cov-2-vaccination-and-the-multi-hit-hypothesis-of-oncogenesis#!/
(A major journal just published a peer-reviewed paper listing eight different ways the vaccines can cause new cancers or make regressed cancers flare up again. The authors then said that since there was so much evidence the jabs promote cancer, the drugmakers should be forced to prove the shots don’t cause cancer in order to continue. “This comprehensive literature review aims to highlight the potential that COVID-19 genetic vaccines, particularly mRNA vaccines, have to fulfill the multi-hit hypothesis of oncogenesis as originally proposed by Sutherland and Bailor in 1984, in that they elicit a pro-tumorigenic milieu favorable to cancer progression and/or (metastatic) recurrence.” Explanatory article here.)Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure
https://www.oncotarget.com/article/28582/text/
(According to the study, spike protein may promote cancer survival and growth through blocking the function of a crucial cancer suppressor gene known as p53. The gene—the most commonly affected by cancer—stops cancer cell growth and encourages DNA repair. Researchers also found that cancer cells containing spike protein subunits displayed increased resistance to chemotherapy. “We saw enhanced cancer cell viability in the presence of SARS-CoV-2 spike S2 subunit after treatment with several chemotherapy agents.” Explanatory articles herehere.)Oncogenesis and autoimmunity as a result of mRNA COVID-19 vaccination
https://www.authorea.com/users/455597/articles/737938-oncogenesis-and-autoimmunity-as-a-result-of-mrna-covid-19-vaccination
(Study shows that repeated injections of mRNA COVID-19 vaccines are taking down immune surveillance for nascent malignant cells while at the same time inducing autoimmunity. Explanatory article here.)Types and Rates of COVID-19 Vaccination in Patients With Newly Diagnosed Microsatellite Stable and Instable Non-Metastatic Colon Cancerhttps://www.cureus.com/articles/260109-types-and-rates-of-covid-19-vaccination-in-patients-with-newly-diagnosed-microsatellite-stable-and-instable-non-metastatic-colon-cancer#!/
(Exposure to the Pfizer mRNA COVID-19 vaccine was associated with a > 6-fold increased risk for this form of cancer. “In this case-control study, we revealed that the mRNA-based COVID-19 vaccine is associated with dMMR non-metastatic colon cancer. The BNT162b2 vaccine is associated with the higher risk of dMMR non-metastatic colon cancer” Explanatory article here. )Review: N1-methyl-pseudouridine (m1Ψ): Friend or foe of cancer?
https://www.sciencedirect.com/science/article/abs/pii/S0141813024022323
(“it has been discovered that the mRNA vaccines inhibit essential immunological pathways, thus impairing early interferon signaling. Within the framework of COVID-19 vaccination, this inhibition ensures an appropriate spike protein synthesis and a reduced immune activation. Evidence is provided that adding 100 % of N1-methyl-pseudouridine (m1Ψ) to the mRNA vaccine in a melanoma model stimulated cancer growth and metastasis, while non-modified mRNA vaccines induced opposite results, thus suggesting that COVID-19 mRNA vaccines could aid cancer development.” Explanatory article here.)SARS-CoV-2 spike S2 subunit inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells
https://www.biorxiv.org/content/10.1101/2024.04.12.589252v1.full
(“In summary, we identified the SARS-CoV-2 spike S2 subunit as a factor that interrupts p53 binding to MDM2 in cancer cells and demonstrated the suppressive effect of SARS-CoV-2 spike S2 on p53 signaling in cancer cells. As loss of p53 function is a known driver of cancer development and confers chemo-resistance, our study provides insight into cellular mechanisms by which SARS-CoV-2 spike S2 may be involved in reducing barriers to tumorigenesis” Explanatory article here.)The impact of BNT162b2 mRNA vaccine on adaptive and innate immune responses
https://www.medrxiv.org/content/10.1101/2021.05.03.21256520v2
(explanatory article: “These COVID-19 mRNA injectable products are causing, yes, causing, immune system dysregulation - and not just in the context of the adaptive system, but in the context of the innate system. Not only that, but these findings provide very good reasons as to why we are seeing resurgences of latent viral infections and other adverse events.”)S2 subunit of SARS-nCoV-2 interacts with tumor suppressor protein p53 and BRCA: an in silico study
https://pubmed.ncbi.nlm.nih.gov/32619819/
(An in silico modeling study that concluded the S2 segment of the SARS-CoV-2 Spike protein could be anticipated to inhibit the p53 and BRCA1/2 tumor surveillance systems. Importantly, the S2 segment has not been found in the body after the infection, however, it is readily produced in large quantities after mRNA COVID-19 vaccination. This suggests C19 infection may not promote cancer growth but C19 vaccine injections may. Explanatory article here.)The CD147 Epitope on SARS CoV2 and the Spike in Cancer, Autoimmunity and Organ Fibrosishttps://www.qeios.com/read/S86J75
("TNFα in partnership with glycosylated CD147 conspires to create the fertile soil for de novo and recurrent cancer. CD147 is present on the spike protein S (virus or vaccine) despite claims to the contrary." Also, "Booster doses and recurrent infections repeatedly stoke the production of TNFα, associated with the spike in the aggressive triple negative form of breast cancer")Increased Age-Adjusted Cancer Mortality After the Third mRNA-Lipid Nanoparticle Vaccine Dose During the COVID-19 Pandemic in Japan
https://assets.cureus.com/uploads/original_article/pdf/196275/20240408-14533-1avkjxd.pdf
("Conclusions: Statistically significant increases in age-adjusted mortality rates of all cancer and some specific types of cancer, namely, ovarian cancer, leukemia, prostate, lip/oral/pharyngeal, pancreatic, and breast cancers, were observed in 2022 after two-thirds of the Japanese population had received the third or later dose of SARS- CoV-2 mRNA-LNP vaccine. These particularly marked increases in mortality rates of these ERα-sensitive cancers may be attributable to several mechanisms of the mRNA-LNP vaccination rather than COVID-19 infection itself or reduced cancer care due to the lockdown.")
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