ALA 8.33% 13.0¢ arovella therapeutics limited

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    Agree Wasabibarako except the Suda ArTiMist research has further relevance.

    For example:

    In healthy adults 31% to 68% of ArTiMist is swallowed and undergoes first pass metabolism. The ArTiMist Researcher then says that this is consistent with that seen in the case of other sublingually administered drugs.

    Also, a fast rate of absorption does not imply fast onset of action. This is because the rate-limiting step can be transport from the mucosal membranes into the systemic circulation.

    See Discussion and in particular reference 27.

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432176/


    Additional references
    https://www.frontiersin.org/articles/10.3389/fphar.2019.01328/full#B7
    https://www.researchgate.net/publication/301987497_Mucoadhesive_Polymers_as_Enabling_Excipients_for_Oral_Mucosal_Drug_Delivery



 
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