Thanks for posting bigdish
CONCLUSIONS
30 mg IMP321 is the RPDT in combination with weekly paclitaxel as a first line chemotherapy treatment of MBC.
6 and 30 mg IMP321 are safe and well tolerated in combination with weekly paclitaxel
IMP321 in combination with paclitaxel shows encouraging DCR (87%)
IMP321 leads to sustainable (> 6months) increase and activation of APC’s (primary PD)
IMP321 leads to sustainable (> 6months) increase in CD8 T Cell and NK cell numbers, together with an improved pre-dose Th1 status ( secondary PD).
This should get the party started. Good luck to all.
ASCO Poster Presentation, page-2
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