Not only are these prophylactic vaccine long term safety data unknown, but are also causing the mutations.
I am concerned that there may be selection pressure on the virus during the vaccination process resulting in escape variants that are even more resilient and transmittable than the current SARSCoV-2. Administering the vaccine to many immunologically naïve individuals could drive many more escape variants, forced to evolve due to immune pressure but I presume that virus genetic mutation will be monitored throughout the trials
https://www.researchgate.net/post/Should-scientists-also-be-cautious-about-vaccine-induced-immune-pressure-driving-mutagenesis-and-advantageous-escape-viral-variants
